UIMC1 Rabbit Polyclonal Antibody (CAB14512)
- SKU:
- CAB14512
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | UIMC1 Rabbit Polyclonal Antibody |
SKU: | CAB14512 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 449-719 of human UIMC1 (NP_057374.3). |
Sequence: | QLSS SETF DLER EVSP GSRD ILDG VRII MADK EVGN KEDA EKEV AIST FSSS NQVS CPLC DQCF PPTK IERH AMYC NGLM EEDT VLTR RQKE AKTK SDSG TAAQ TSLD IDKN EKCY LCKS LVPF REYQ CHVD SCLQ LAKA DQGD GPEG SGRA CSTV EGKW QQRL KNPK EKGH SEGR LLSF LEQS EHKT SDAD IKSS ETGA FRVP SPGM EEAG CSRE MQSS FTRR DLNE SPVK SFVS ISEA TDCL VDFK KQVT VQPG SRTR TKAG RGRR RKF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RAP80; X2HRIP110; UIMC1 |
Positive Sample: | DU145,293T,HeLa,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 80kDa |
Observed MW: | 102kDa |
This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 51720 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |