The UIMC1 Polyclonal Antibody (CAB14512) is a high-quality antibody designed for research involving the UIMC1 protein. UIMC1 is a critical player in DNA repair and cell cycle regulation, making it an important target for studies in genetics and cancer research. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the UIMC1 protein, researchers can accurately detect and analyze its expression in a variety of cell types.
The UIMC1 Polyclonal Antibody is ideal for investigations into DNA damage response pathways, cell proliferation, and the development of potential targeted cancer therapies. Its ability to target UIMC1 makes it a valuable tool for understanding the molecular mechanisms underlying cancer progression and genetic instability. Overall, the UIMC1 Polyclonal Antibody is a reliable research reagent that can facilitate breakthroughs in cancer biology, genetics, and personalized medicine.
Product Name:
UIMC1 Rabbit Polyclonal Antibody
SKU:
CAB14512
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 449-719 of human UIMC1 (NP_057374.3).
This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51720
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UIMC1 Rabbit pAb (CAB14512) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
