The UHRF2 Polyclonal Antibody (CAB2344) is a valuable tool for researchers studying UHRF2, a key protein involved in epigenetic regulation and cellular processes such as DNA methylation and gene expression. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically targeting the UHRF2 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in cancer biology, epigenetics, and cell cycle regulation.UHRF2, a member of the UHRF protein family, plays a critical role in maintaining genome stability and epigenetic marks through its interactions with DNA methyltransferases and histone modifying enzymes.
Dysregulation of UHRF2 has been linked to various diseases, including cancer and developmental disorders, highlighting its importance as a potential therapeutic target. Studying the function and regulation of UHRF2 can provide insights into disease mechanisms and aid in the development of targeted therapies aimed at restoring normal cellular functions.
Product Name:
Uhrf2 Rabbit Polyclonal Antibody
SKU:
CAB2344
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2).
Enables histone binding activity. Predicted to be involved in several processes, including maintenance of DNA methylation; protein autoubiquitination; and regulation of cell cycle. Located in heterochromatin and nucleus. Is expressed in several structures, including central nervous system; ear; early conceptus; female reproductive system; and urinary system. Orthologous to human UHRF2 (ubiquitin like with PHD and ring finger domains 2).
Purification Method:
Affinity purification
Gene ID:
109113
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse thymus, using Uhrf2 antibody (CAB2344) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
