The UHRF2 Polyclonal Antibody (CAB13647) is a valuable tool for researchers studying UHRF2, a key protein involved in epigenetic regulation and DNA methylation. This antibody, produced in rabbits, is highly specific to human UHRF2 and has been validated for use in Western blot applications. By targeting the UHRF2 protein, this antibody enables accurate detection and analysis, making it an essential component for studies in epigenetics, cancer research, and cell cycle regulation.UHRF2 is known for its role in maintaining DNA methylation patterns and gene expression, which are crucial for normal cell function and differentiation.
Dysregulation of UHRF2 has been implicated in various diseases, including cancer and developmental disorders. By studying the function and regulation of UHRF2, researchers can gain valuable insights into disease mechanisms and potential therapeutic targets related to epigenetic modifications.Overall, the UHRF2 Polyclonal Antibody (CAB13647) offers researchers a reliable tool for investigating the complex role of UHRF2 in epigenetic processes and disease development. Its specificity and sensitivity make it an invaluable resource for advancing our understanding of epigenetic regulation and its implications for human health.
Product Name:
Uhrf2 Rabbit Polyclonal Antibody
SKU:
CAB13647
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2).
Enables histone binding activity. Predicted to be involved in several processes, including maintenance of DNA methylation; protein autoubiquitination; and regulation of cell cycle. Located in heterochromatin and nucleus. Is expressed in several structures, including central nervous system; ear; early conceptus; female reproductive system; and urinary system. Orthologous to human UHRF2 (ubiquitin like with PHD and ring finger domains 2).
Purification Method:
Affinity purification
Gene ID:
109113
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Uhrf2 antibody (CAB13647) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
