UHRF2 Rabbit Polyclonal Antibody (CAB13602)
- SKU:
- CAB13602
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | UHRF2 Rabbit Polyclonal Antibody |
SKU: | CAB13602 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 441-622 of human UHRF2 (NP_690856.1). |
Sequence: | IVPS NHYG PIPG IPVG STWR FRVQ VSEA GVHR PHVG GIHG RSND GAYS LVLA GGFA DEVD RGDE FTYT GSGG KNLA GNKR IGAP SADQ TLTN MNRA LALN CDAP LDDK IGAE SRNW RAGK PVRV IRSF KGRK ISKY APEE GNRY DGIY KVVK YWPE ISSS HGFL VWRY LLRR DDVE PAPW TS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NIRF; URF2; RNF107; TDRD23; UHRF2 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 90kDa |
Observed MW: | Refer to figures |
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
Purification Method: | Affinity purification |
Gene ID: | 115426 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |