The UHRF1BP1 Polyclonal Antibody (PAC020827) is a valuable tool for researchers studying the UHRF1BP1 protein, which plays a crucial role in epigenetic regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to UHRF1BP1, it enables detection and analysis in a variety of cell types, making it ideal for studies in epigenetics, cancer research, and beyond.UHRF1BP1 is a key player in maintaining DNA methylation patterns and gene expression regulation, making it a promising target for investigating various diseases, including cancer and developmental disorders.
Understanding the function of UHRF1BP1 is essential for unraveling its role in epigenetic mechanisms and identifying potential therapeutic strategies for diseases associated with aberrant DNA methylation.Overall, the UHRF1BP1 Polyclonal Antibody (PAC020827) is a reliable tool for researchers seeking to explore the functions of UHRF1BP1 and its implications in epigenetic processes and disease pathogenesis.
Antibody Name:
UHRF1BP1 Antibody (PACO20827)
Antibody SKU:
PACO20827
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human UHRF1BP1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20827(UHRF1BP1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20827(UHRF1BP1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
UHRF1BP1 (UHRF1 binding protein 1) is a 1,440 amino acid, protein that interacts with UHRF1 and may act as a negative regulator of cell growth. The UHRF1BP1 protein has been identified as a possible risk loci for systemic lupus erythematosus. The UHRF1BP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish and C.elegans, and maps to human chromosome 6p21.31.
Synonyms:
UHRF1 binding protein 1
UniProt Protein Function:
UHRF1BP1: May act as a negative regulator of cell growth.Protein type: Unknown functionChromosomal Location of Human Ortholog: 6p21Molecular Function: histone deacetylase binding; identical protein binding; protein binding
