The UGT3A2 Polyclonal Antibody (CAB7611) is specifically designed for research involving UGT3A2, a key enzyme involved in phase II metabolism of xenobiotics and endogenous compounds. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications including Western blot and immunohistochemistry.UGT3A2, a member of the UDP-glucuronosyltransferase family, is known for its role in detoxification processes within the liver and other tissues. Understanding the expression and function of UGT3A2 is essential for studying drug metabolism, toxicology, and drug-drug interactions.
Research on UGT3A2 can provide valuable insights into how different compounds are metabolized and cleared from the body, with implications for personalized medicine and drug development.The UGT3A2 Polyclonal Antibody offers researchers a reliable tool for detecting and quantifying UGT3A2 expression in various biological samples, aiding in the investigation of drug metabolism pathways and their impact on human health. Its versatility and specificity make it an ideal choice for studies in pharmacology, toxicology, and clinical research.
Product Name:
UGT3A2 Rabbit Polyclonal Antibody
SKU:
CAB7611
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-300 of human UGT3A2 (NP_777574.2).
B cells,Jurkat,HepG2,Mouse kidney,Mouse spleen,Rat liver,Rat spleen
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Single-pass type I membrane protein.
Calculated MW:
60kDa
Observed MW:
75kDa
Enables UDP-glycosyltransferase activity. Acts upstream of or within cellular response to genistein. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle.
Purification Method:
Affinity purification
Gene ID:
167127
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UGT3A2 antibody (CAB7611) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
