The UGT2B15 Polyclonal Antibody (CAB16657) is a valuable tool for researchers studying the UGT2B15 enzyme, which plays a crucial role in phase II drug metabolism. This antibody, produced in rabbits, shows high reactivity to human samples and has been validated for use in Western blot applications. By specifically binding to the UGT2B15 protein, this antibody enables the detection and analysis of this enzyme in various cell types, making it essential for studies in pharmacology and drug metabolism research.UGT2B15 is a member of the UDP-glucuronosyltransferase family involved in the conjugation of lipophilic substances with glucuronic acid, facilitating their elimination from the body.
Understanding the activity of UGT2B15 is vital for predicting drug clearance rates and potential drug-drug interactions, particularly in the development of personalized medicine approaches. Research into the function and regulation of UGT2B15 can provide valuable insights into drug metabolism variability in individuals, leading to safer and more effective pharmacotherapy strategies.
Product Name:
UGT2B15 Rabbit Polyclonal Antibody
SKU:
CAB16657
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human UGT2B15 (NP_001067.2).
This gene encodes a glycosyltransferase that is invovled in the metabolism and elimination of toxic compounts, both endogenous and of xenobiotic origin. This gene plays a role in the regulation of estrogens and androgens. This locus is present in a cluster of similar genes and pseudogenes on chromosome 4.
Purification Method:
Affinity purification
Gene ID:
7366
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UGT2B15 Rabbit pAb (CAB16657) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
