UGT1A9 Rabbit Polyclonal Antibody (CAB1661)
- SKU:
- CAB1661
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | UGT1A9 Rabbit Polyclonal Antibody |
SKU: | CAB1661 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-250 of human UGT1A9 (NP_066307.1). |
Sequence: | GKLL VVPM DGSH WFTM RSVV EKLI LRGH EVVV VMPE VSWQ LGRS LNCT VKTY STSY TLED LDRE FKAF AHAQ WKAQ VRSI YSLL MGSY NDIF DLFF SNCR SLFK DKKL VEYL KESS FDAV FLDP FDNC GLIV AKYF SLPS VVFA RGIL CHYL EEGA QCPA PLSY VPRI LLGF SDAM TFKE RVRN HIMH LEEH LLCH RFFK NALE IASE ILQT PVTE YDLY SHTS I |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | LUGP4; UDPGT; UGT1I; HLUGP4; UGT-1I; UGT1-9; UGT1.9; UGT1AI; UGT1-09; UGT1A9S; UDPGT 1-9; UGT1A9 |
Positive Sample: | Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome, Single-pass membrane protein. |
Calculated MW: | 60kDa |
Observed MW: | 55kDa |
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols.
Purification Method: | Affinity purification |
Gene ID: | 54600 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |