UGT1A6 Rabbit Polyclonal Antibody (CAB10033)
- SKU:
- CAB10033
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | UGT1A6 Rabbit Polyclonal Antibody |
SKU: | CAB10033 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 65-270 of human UGT1A6 (NP_001063.2). |
Sequence: | LLLK ESKY YTRK IYPV PYDQ EELK NRYQ SFGN NHFA ERSF LTAP QTEY RNNM IVIG LYFI NCQS LLQD RDTL NFFK ESKF DALF TDPA LPCG VILA EYLG LPSV YLFR GFPC SLEH TFSR SPDP VSYI PRCY TKFS DHMT FSQR VANF LVNL LEPY LFYC LFSK YEEL ASAV LKRD VDII TLYQ KVSV WLLR YDFV LEYP RPVM PN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GNT1; UGT1; HLUGP; UDPGT; UGT1A; UGT1C; UGT1E; UGT1F; HLUGP1; UGT-1A; UGT-1C; UGT-1E; UGT-1F; UGT1.1; UGT1.3; UGT1.5; UGT1.6; UGT1A1; UGT1A3; UGT1A5; UGT1-01; UGT1-03; UGT1-05; UGT1-06; UGT1A6S; hUG-BR1; UDPGT 1-6; UGT1A6 |
Positive Sample: | HeLa,HepG2,SW480,MCF7,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome, Single-pass membrane protein. |
Calculated MW: | 61kDa |
Observed MW: | 75kDa |
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 54578 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |