UGT1A1 Rabbit Polyclonal Antibody (CAB6186)

SKU:: CAB6186
UPC:
Product Type:: Antibody
Reactivity:: Human; Mouse; Rat
Host Species:: Rabbit
Isotype:: IgG
Antibody Type:: Polyclonal Antibody
Research Area:: Cell Biology

€139 - €419

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UGT1A1 Rabbit Polyclonal Antibody (CAB6186)

The UGT1A1 Polyclonal Antibody (CAB6186) is a crucial tool for researchers studying the UGT1A1 enzyme, which plays a key role in the metabolism and detoxification of various endogenous and exogenous compounds in the body. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the UGT1A1 enzyme, researchers can accurately detect and analyze its expression in a variety of cell types, making it an ideal choice for studies in pharmacology, toxicology, and liver metabolism.

UGT1A1 is a member of the UDP-glucuronosyltransferase enzyme family, responsible for catalyzing the glucuronidation of a wide range of substances, including bilirubin, drugs, and environmental toxins. Dysregulation of UGT1A1 activity has been implicated in various diseases, such as Gilbert's syndrome and Crigler-Najjar syndrome, highlighting the importance of understanding its function in health and disease. By gaining insights into the role of UGT1A1, researchers can potentially develop new therapeutic approaches for conditions related to impaired glucuronidation processes.