Similarly, the UGGT1 Polyclonal Antibody (CAB4866) offered by Assay Genie is a valuable tool for researchers studying UGGT1, an enzyme involved in protein glycosylation and quality control in the endoplasmic reticulum. This antibody, generated in rabbits, exhibits high specificity for human samples and is suitable for Western blotting applications.Recognizing and binding to the UGGT1 enzyme, this antibody enables precise detection and analysis of UGGT1 levels in diverse cell types. This feature makes it an essential reagent for research in cell biology, protein quality control, and ER stress response pathways.The UGGT1 enzyme is crucial for maintaining protein homeostasis and preventing misfolded protein accumulation, making it a key player in cellular processes related to protein folding and degradation.
Dysfunction of UGGT1 has been implicated in various diseases, including neurodegenerative disorders and cancer, highlighting the importance of studying this enzyme for potential therapeutic interventions.In summary, the UGGT1 Polyclonal Antibody (CAB4866) from Assay Genie is a reliable tool for investigating UGGT1 function and its role in protein quality control mechanisms, offering valuable insights into cellular processes and disease pathways.
Product Name:
UGGT1 Rabbit Polyclonal Antibody
SKU:
CAB4866
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1456-1555 of human UGGT1 (NP_064505.1).
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.
Purification Method:
Affinity purification
Gene ID:
56886
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UGGT1 antibody (CAB4866) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
