UGDH Rabbit Polyclonal Antibody (CAB13559)
- SKU:
- CAB13559
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | UGDH Rabbit Polyclonal Antibody |
SKU: | CAB13559 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-494 of human UGDH (NP_003350.1). |
Sequence: | EGTA IKDL KNPD RVLI GGDE TPEG QRAV QALC AVYE HWVP REKI LTTN TWSS ELSK LAAN AFLA QRIS SINS ISAL CEAT GADV EEVA TAIG MDQR IGNK FLKA SVGF GGSC FQKD VLNL VYLC EALN LPEV ARYW QQVI DMND YQRR RFAS RIID SLFN TVTD KKIA ILGF AFKK DTGD TRES SSIY ISKY LMDE GAHL HIYD PKVP REQI VVDL SHPG VSED DQVS RLVT ISKD PYEA CDGA HAVV ICTE WDMF KELD YERI HKKM LKPA FIFD GRRV LDGL HNEL QTIG FQIE TIGK KVSS KRIP YAPS GEIP KFSL QDPP NKKP KV |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | GDH; UGD; DEE84; EIEE84; UDPGDH; UDP-GlcDH; UGDH |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular exosome, nucleoplasm, nucleus |
Calculated MW: | 55kDa |
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7358 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |