The UGDH Polyclonal Antibody (CAB13559) is a valuable tool for researchers studying UGDH, an enzyme involved in the metabolism of glucose and the production of UDP-glucose, a key molecule in carbohydrate biosynthesis. This antibody, produced in rabbits, shows high reactivity with human samples and is specifically validated for use in Western blot applications.UGDH plays a crucial role in various cellular processes, including cell growth, proliferation, and differentiation, making it an important target for investigation in the fields of metabolism, cancer biology, and carbohydrate metabolism disorders. By binding to the UGDH protein, this antibody enables precise detection and analysis of UGDH expression in different cell types, facilitating in-depth research and exploration of its functional role in health and disease.
Researchers interested in understanding the metabolic pathways and molecular mechanisms governed by UGDH will find this polyclonal antibody to be a reliable tool for their studies. Its application extends to a wide range of research areas, from biochemistry and molecular biology to cancer research and metabolic disorders. By utilizing this antibody, scientists can unravel the complex roles of UGDH in cellular function and disease development, leading to potential therapeutic advancements and insights into metabolic regulation.
Product Name:
UGDH Rabbit Polyclonal Antibody
SKU:
CAB13559
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 165-494 of human UGDH (NP_003350.1).
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7358
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded rat liver using UGDH Rabbit pAb (CAB13559) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
