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UGDH Monoclonal Antibody [PAT2G11AT] (CPAB0243)

SKU:
CPAB0243
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT2G11AT
Applications:
WB
ELISA
FC
$179
Frequently bought together:

Description

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UGDH Monoclonal Antibody [PAT2G11AT] (CPAB0243)

The UGDH Polyclonal Antibody (CPAB0243) is a vital tool for researchers studying UGDH, an enzyme involved in the metabolism of glucose and the biosynthesis of hyaluronic acid. This rabbit-raised antibody exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blotting applications. By targeting the UGDH protein, this antibody enables precise detection and analysis in various cell types, facilitating in-depth investigations in fields such as biochemistry and molecular biology.

UGDH, or UDP-glucose 6-dehydrogenase, plays a crucial role in cellular processes by converting UDP-glucose to UDP-glucuronic acid, a key component in the production of hyaluronic acid. Dysregulation of UGDH has been implicated in various diseases, including cancer and metabolic disorders, making it a promising therapeutic target for drug development. Researchers studying UGDH can gain valuable insights into its function and potential therapeutic implications with the help of this high-quality antibody.

Product Name:UGDH Antibody
Product Sku:CPAB0243
Size:5μg
Host Species:Mouse
Immunogen:Anti-human UGDH mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human UGDH amino acids 1-494 purified from Ecoli.
Clone:PAT2G11AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:UGDH antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:UGDH is part of the UDP-glucose/GDP-mannose dehydrogenase family and is a widely expressed enzyme localized in the liver. UGDH transfers UDP-glucose to UDP-glucuronate and thus takes part in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated products are ordinary molecules of the extracellular matrix and participate in signal transduction, cell migration, and cancer growth and metastasis.
Synonyms:GDH, UDP-GlcDH, UDPGDH, UGD, EC 1.1.1.22, UDP-Glc dehydrogenase, UDP-glucose 6-dehydrogenase, UGDH.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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