The UGCG Polyclonal Antibody (CAB6317) is a research tool specifically designed for studying UGCG, a key enzyme in sphingolipid metabolism. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding to the UGCG protein, this antibody allows for the detection and analysis of UGCG in a variety of cell types, making it an ideal tool for research in lipid metabolism, cancer biology, and cellular signaling pathways.UGCG, also known as UDP-glucose ceramide glucosyltransferase, plays a crucial role in the biosynthesis of glycosphingolipids, which are important components of cell membranes and are involved in various cellular functions.
Dysregulation of UGCG has been implicated in diseases such as cancer, neurodegenerative disorders, and metabolic disorders. By studying the activity of UGCG, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for their treatment. The UGCG Polyclonal Antibody is a valuable tool for researchers seeking to further their understanding of UGCG and its role in health and disease. Its high specificity and sensitivity make it a reliable choice for Western blotting experiments, enabling accurate and reproducible results in the laboratory.
Product Name:
UGCG Rabbit Polyclonal Antibody
SKU:
CAB6317
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UGCG (NP_003349.1).
This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids.
Purification Method:
Affinity purification
Gene ID:
7357
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells using UGCG Rabbit pAb(CAB6317) at 1:2000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:60s.
