The UFM1 Polyclonal Antibody (CAB15843) is a valuable tool for researchers studying the UFM1 protein, an essential component of the UFM1 conjugation system involved in protein modification and regulation. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting UFM1 in human samples, making it suitable for Western blot applications.UFM1 is a small protein modifier that plays a critical role in cellular processes such as protein folding, quality control, and stress response. Dysregulation of the UFM1 conjugation system has been implicated in various diseases, including neurodegenerative disorders and cancer.
By targeting UFM1 with this polyclonal antibody, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.The UFM1 Polyclonal Antibody is an essential tool for investigating the functions of UFM1 in cellular pathways and disease states. Its versatility and reliability make it an ideal choice for studies in molecular biology, biochemistry, and biomedicine. Research using this antibody may lead to a better understanding of UFM1-mediated processes and the development of novel strategies for disease intervention.
Product Name:
UFM1 Rabbit Polyclonal Antibody
SKU:
CAB15843
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-63 of human UFM1 (NP_057701.1).
UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M; MIM 603173) (Komatsu et al., 2004 [PubMed 15071506]).
Purification Method:
Affinity purification
Gene ID:
51569
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using UFM1 Rabbit pAb (CAB15843) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
