UFD1L Rabbit Polyclonal Antibody (CAB3255)
- SKU:
- CAB3255
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | UFD1L Rabbit Polyclonal Antibody |
SKU: | CAB3255 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of human UFD1L (NP_005650.2). |
Sequence: | MFSF NMFD HPIP RVFQ NRFS TQYR CFSV SMLA GPND RSDV EKGG KIIM PPSA LDQL SRLN ITYP MLFK LTNK NSDR MTHC GVLE FVAD EGIC YLPH WMMQ NLLL EEGG LVQV ESVN LQVA TYSK FQPQ SPDF LDIT NPKA VLEN ALRN FACL TTGD VIAI NYNE KIYE LRVM ETKP DKAV SIIE CDMN VDFD APLG YKEP ERQV QHEE STEG EADH SGYA GELG FRAF SGSG NRLD GKKK GVEP SPSP IKPG DIKR GIPN YEFK LGKI TFIR NSRP LVKK VEED EAGG RFVA FSGE GQSL RKKG RKP |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | UFD1L |
Positive Sample: | MCF7,A-431,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, cytosol. |
Calculated MW: | 35kDa |
Observed MW: | 37kDa |
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
Purification Method: | Affinity purification |
Gene ID: | 7353 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |