The UFC1 Polyclonal Antibody (CAB13192) is specifically designed for research involving UFC1, a protein involved in regulating protein degradation and the cell cycle. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the UFC1 protein, this antibody allows for the detection and analysis of UFC1 in various cell types, making it an ideal tool for studies in molecular biology and cell cycle regulation.UFC1 is a critical component of the ubiquitin-proteasome system, which plays a key role in maintaining protein homeostasis within cells.
Dysregulation of this system can lead to numerous diseases, including cancer and neurodegenerative disorders. Research into the function of UFC1 is essential for understanding how protein degradation is regulated and how it impacts cellular processes. This antibody offers researchers a valuable tool for investigating the role of UFC1 in health and disease, aiding in the development of potential therapeutic interventions targeting this pathway.
Product Name:
UFC1 Rabbit Polyclonal Antibody
SKU:
CAB13192
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human UFC1 (NP_057490.2).
UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1; MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]).
Purification Method:
Affinity purification
Gene ID:
51506
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UFC1 Rabbit pAb (CAB13192) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
