The UBXN2A Polyclonal Antibody (PAC060861) is a valuable tool for researchers studying UBXN2A, a protein involved in various cellular processes, including protein degradation and immune response regulation. This antibody, produced in rabbits, shows high specificity and sensitivity for UBXN2A in human samples, making it suitable for use in Western blotting and immunohistochemistry.UBXN2A, a member of the UBX domain-containing protein family, is known for its role in the ubiquitin-proteasome system, where it functions as a substrate adaptor for the p97 ATPase. Additionally, UBXN2A has been implicated in modulating immune signaling pathways, suggesting its potential relevance in disease mechanisms and therapeutic targeting.
By using the UBXN2A Polyclonal Antibody, researchers can investigate the expression and localization of UBXN2A in various cell types and tissues, providing insight into its biological functions and potential implications in disease development. This antibody is a valuable tool for studies in molecular biology, immunology, and cell biology, offering new opportunities for unraveling the complexity of UBXN2A-mediated processes.
Antibody Name:
UBXN2A Antibody (PACO60861)
Antibody SKU:
PACO60861
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human UBX domain-containing protein 2A protein (15-162AA)
Immunofluorescence staining of HepG2 cells with PACO60861 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
cytosol, nucleus, protein phosphatase regulator activity, ubiquitin binding, autophagosome assembly, Golgi organization, membrane fusion, nuclear envelope reassembly, proteasome-mediated ubiquitin-dependent protein catabolic process
Synonyms:
UBX domain-containing protein 2A (UBX domain-containing protein 4), UBXN2A, UBXD4
