The UBR7 Polyclonal Antibody (CAB15464) is a crucial tool for researchers studying the UBR7 protein, a key player in the ubiquitin-proteasome system responsible for protein degradation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot experiments.UBR7's role in regulating protein turnover and maintaining cellular homeostasis highlights its importance in various biological processes, including cell cycle progression, DNA repair, and stress response. By targeting the UBR7 protein, researchers can gain insights into its function and potential therapeutic applications in diseases related to protein misfolding and degradation, such as neurodegenerative disorders and cancer.
With its ability to detect and analyze UBR7 in different cell types, the UBR7 Polyclonal Antibody is a valuable tool for investigations in molecular biology, cell biology, and biomedical research. Its versatility and reliability make it an essential component in the quest to unravel the complexities of protein degradation pathways and their implications in health and disease.
Product Name:
UBR7 Rabbit Polyclonal Antibody
SKU:
CAB15464
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 76-425 of human UBR7 (NP_786924.2).
This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome.
Purification Method:
Affinity purification
Gene ID:
55148
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UBR7 Rabbit pAb (CAB15464) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
