UBR5 Rabbit Polyclonal Antibody (CAB13816)
- SKU:
- CAB13816
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | UBR5 Rabbit Polyclonal Antibody |
SKU: | CAB13816 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 550-760 of human UBR5 (NP_056986.2). |
Sequence: | SISA GIPK VGVL MESV WNMN DSCR FQLR SPES LKNM EKAS KTTE AKPE SKQE PVKT EMGP PPSP ASTC SDAS SIAS SASM PYKR RRST PAPK EEEK VNEE QWSL REVV FVED VKNV PVGK VLKV DGAY VAVK FPGT SSNT NCQN SSGP DADP SSLL QDCR LLRI DELQ VVKT GGTP KVPD CFQR TPKK LCIP EKTE ILAV NVDS KGVH AVL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DD5; EDD; HYD; EDD1; UBR5 |
Positive Sample: | U-87MG,293T,Jurkat,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 309kDa |
Observed MW: | 300kDa |
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.
Purification Method: | Affinity purification |
Gene ID: | 51366 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |