UBQLN3 Rabbit Polyclonal Antibody (CAB17697)
- SKU:
- CAB17697
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | UBQLN3 Rabbit Polyclonal Antibody |
SKU: | CAB17697 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 306-620 of human UBQLN3 (NP_059509.1). |
Sequence: | WTST HGGS GSRQ GRQD GDQD APDI RNRF PNFL GIIR LYDY LQQL HENP QSLG TYLQ GTAS ALSQ SQEP PPSV NRVP PSSP SSQE PGSG QPLP EESV AIKG RSSC PAFL RYPT ENST GQGG DQDG AGKS STGH STNL PDLV SGLG DSAN RVPF APLS FSPT AAIP GIPE PPWL PSPA YPRS LRPD GMNP APQL QDEI QPQL PLLM HLQA AMAN PRAL QALR QIEQ GLQV LATE APRL LLWF MPCL AGTG SVAG GIES REDP LMSE DPLP NPPP EVFP ALDS AELG FLSP PFLH MLQD LVST NPQQ LQPE AHFQ VQL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | TUP-1; UBQLN3 |
Positive Sample: | PC-3,Mouse testis,Rat testis,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 71kDa |
Observed MW: | 71kDa |
This gene encodes a ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis. It has been suggested that this gene may regulate cell-cycle progression during spermatogenesis, however, it has been shown that the ortholgous mouse gene is dispensable for embryonic development and spermatogenesis.
Purification Method: | Affinity purification |
Gene ID: | 50613 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |