The Ubiquitin Monoclonal Antibody (MACO0394) offered by Assay Genie is a valuable tool for researchers studying the ubiquitin-proteasome system, a critical pathway for protein degradation and regulation. This monoclonal antibody, produced in mice, is highly specific for detecting ubiquitin in various samples and is validated for use in immunofluorescence and immunohistochemistry applications.Ubiquitin is a small protein that plays a crucial role in tagging proteins for degradation, as well as regulating various cellular processes such as DNA repair, cell cycle progression, and signal transduction. Dysregulation of the ubiquitin-proteasome system has been implicated in various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.
Understanding the mechanisms of ubiquitin signaling and protein degradation is essential for developing targeted therapies for these diseases.The Ubiquitin Monoclonal Antibody (MACO0394) from Assay Genie offers high sensitivity and specificity for detecting ubiquitin, enabling researchers to investigate the role of this important molecule in various biological processes. With its broad applications in cell biology, biochemistry, and disease research, this antibody is a valuable tool for advancing our understanding of the ubiquitin-proteasome system and its implications in human health and disease.
Product Name:
Anti-Ubiquitin Antibody
Product Sku:
MACO0394
Size:
50ug
Host Species:
Mouse
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:5000, IHC:1:50-1:500
Species Reactivity:
Human,Mouse,Rat
Immunogen:
Synthetic Peptide of Ubiquitin
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Clonality:
Monoclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Background:
Synonyms:
Immunohistochemical analysis of paraffin-embedded Human Stomach Carcinoma Tissue using Ubiquitin Mouse mAb diluted at 1:200.
Western blot analysis of 1) Hela Cell Lysate, 2) 3T3 Cell Lysate, 3) Rat Brain Tissue Lysate using Ubiquitin Mouse mAb diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Ubiquitin Mouse mAb diluted at 1:200.