The Ubiquitin D Rabbit Monoclonal Antibody (CAB9005) is a valuable tool for research studies involving ubiquitin D, a protein involved in the regulation of various cellular processes, including protein degradation and DNA repair. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications. By targeting ubiquitin D, researchers can detect and analyze its expression levels in different cell types, providing insights into its role in various biological pathways.Ubiquitin D is an essential component of the ubiquitin-proteasome system, which is responsible for the selective degradation of proteins involved in cell cycle regulation, signal transduction, and DNA repair. Dysregulation of ubiquitin D has been implicated in the development of various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.
Therefore, studying the function of ubiquitin D using this antibody is crucial for understanding its contribution to disease pathogenesis and for identifying potential therapeutic targets.Overall, the Ubiquitin D Rabbit Monoclonal Antibody (CAB9005) serves as a valuable tool for researchers interested in unraveling the roles of ubiquitin D in cellular processes and disease development. Its high specificity and sensitivity make it a reliable reagent for studies in cell biology, biochemistry, and molecular biology, ultimately contributing to the advancement of knowledge in the field of ubiquitin research.
Product Name:
FAT10/UBD Rabbit Monoclonal Antibody
SKU:
CAB9005
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human FAT10/UBD (O15205).
This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types.
Purification Method:
Affinity purification
Gene ID:
10537
Clone Number:
ARC1379
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FAT10/UBD Rabbit mAb (CAB9005) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
