The Ubiquitin D Polyclonal Antibody (CAB5491) is a powerful tool for researchers studying ubiquitin-mediated cellular processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications. By binding to ubiquitin D, this antibody enables accurate detection and analysis in a variety of cell types, facilitating in-depth investigations into ubiquitin signaling pathways and their roles in cellular physiology.Ubiquitin D is a crucial player in the ubiquitin system, which regulates protein degradation, DNA repair, and various signaling pathways within the cell. Dysregulation of ubiquitin-mediated processes has been implicated in a wide range of diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.
Therefore, understanding the function and regulation of ubiquitin D is essential for developing targeted therapies and interventions aimed at modulating these pathways for therapeutic benefit.Overall, the Ubiquitin D Polyclonal Antibody (CAB5491) offers researchers a reliable tool for studying ubiquitin biology and its implications in health and disease. Its specificity, sensitivity, and versatility make it a valuable asset for studies in molecular biology, cell biology, and biomedical research.
Product Name:
FAT10/UBD Rabbit Polyclonal Antibody
SKU:
CAB5491
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human FAT10/FAT10/UBD (NP_006389.2).
This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types.
Purification Method:
Affinity purification
Gene ID:
10537
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse liver, using FAT10/FAT10/UBD antibody (CAB5491) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
