UBE4B Rabbit Polyclonal Antibody (CAB17609)
- SKU:
- CAB17609
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | UBE4B Rabbit Polyclonal Antibody |
SKU: | CAB17609 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-250 of human UBE4B (NP_006039.2). |
Sequence: | EVDE NDRR EKRS LSDK EPSS GPEV SEEQ ALQL VCKI FRVS WKDR DRDV IFLS SLSA QFKQ NPKE VFSD FKDL IGQI LMEV LMMS TQTR DENP FASL TATS QPIA AAAR SPDR NLLL NTGS N |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | E4; UFD2; HDNB1; UBOX3; UFD2A; UBE4B |
Positive Sample: | Raji,OVCAR3,HeLa,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, nucleus |
Calculated MW: | 146kDa |
Observed MW: | 146kDa |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10277 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |