UBE4A Rabbit Polyclonal Antibody (CAB3354)
- SKU:
- CAB3354
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | UBE4A Rabbit Polyclonal Antibody |
SKU: | CAB3354 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 797-1066 of human UBE4A (NP_001191006.1). |
Sequence: | FLLD EAIQ YLSK IKIQ QIEK DRGE WDSL TPEA RREK EAGL QMFG QLAR FHNI MSNE TIGT LAFL TSEI KSLF VHPF LAER IISM LNYF LQHL VGPK MGAL KVKD FSEF DFKP QQLV SDIC TIYL NLGD EENF CATV PKDG RSYS PTLF AQTV RVLK KINK PGNM IMAF SNLA ERIK SLAD LQQQ EEET YADA CDEF LDPI MSTL MCDP VVLP SSRV TVDR STIA RHLL SDQT DPFN RSPL TMDQ IRPN TELK EKIQ RWLA ERKQ QKEQ LE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 |
Synonyms: | E4; UFD2; UBOX2; NEDHMS; UBE4A |
Positive Sample: | Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 123kDa |
Observed MW: | 123kDa |
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9354 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |