The UBE2W Polyclonal Antibody (CAB16691) is a valuable tool for researchers studying UBE2W, a key enzyme involved in protein ubiquitination processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blot applications. By binding to the UBE2W protein, this antibody enables accurate detection and analysis in various cell types, facilitating detailed research in the fields of molecular biology and biochemistry.UBE2W, also known as ubiquitin-conjugating enzyme E2W, plays a crucial role in the controlled degradation of proteins through the ubiquitin-proteasome system.
Dysregulation of this system has been linked to various diseases, including cancer and neurodegenerative disorders. As such, investigating the function of UBE2W is essential for understanding the mechanisms underlying these conditions and developing targeted therapies.Overall, the UBE2W Polyclonal Antibody is an essential tool for researchers investigating protein ubiquitination pathways and their implications in disease development. Its high specificity and reliability make it a valuable asset for studies aiming to elucidate the roles of UBE2W in cellular processes and pathological conditions.
Product Name:
UBE2W Rabbit Polyclonal Antibody
SKU:
CAB16691
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-110 of human UBE2W (NP_001001481.2).
This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55284
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UBE2W Rabbit pAb (CAB16691) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
