The UBE2U Polyclonal Antibody (CAB8376) is a valuable tool for research involving UBE2U, a key enzyme involved in the ubiquitination pathway. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for Western blot applications. It binds specifically to the UBE2U protein, enabling precise detection and analysis in various cell types.UBE2U is essential for the regulation of protein degradation through the ubiquitin-proteasome system, playing a crucial role in cellular processes such as DNA repair, cell cycle progression, and signal transduction.
Dysregulation of UBE2U has been linked to various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. Understanding the function and regulation of UBE2U is vital for developing targeted therapies and investigating its potential as a biomarker for disease.Researchers in the fields of biochemistry, cell biology, and molecular biology will benefit from the use of the UBE2U Polyclonal Antibody in their experiments, paving the way for advancements in understanding the role of UBE2U in health and disease.
Product Name:
UBE2U Rabbit Polyclonal Antibody
SKU:
CAB8376
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-226 of human UBE2U (NP_689702.1).
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in DNA repair; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be part of HULC complex.
Purification Method:
Affinity purification
Gene ID:
148581
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using UBE2U Rabbit pAb (CAB8376) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
