The UBE2S Polyclonal Antibody (CAB18064) is a valuable tool for researchers studying UBE2S, a key protein involved in the regulation of cell cycle progression and DNA repair. Raised in rabbits, this antibody is highly specific and reacts well with human samples, making it ideal for use in Western blot applications. By binding to UBE2S, the antibody allows for the detection and analysis of this important protein in various cell types, providing valuable insights into its function in cellular processes.
UBE2S is a crucial component of the ubiquitin-proteasome system, playing a central role in the degradation of proteins involved in cell cycle control and DNA damage response. Dysregulation of UBE2S has been linked to various diseases, including cancer, making it a promising target for therapeutic interventions. Understanding the role of UBE2S in these pathological conditions is essential for the development of targeted treatments that exploit its functions in disease progression.
Product Name:
[KO Validated] UBE2S Rabbit Polyclonal Antibody
SKU:
CAB18064
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 122-221 of human UBE2S (NP_055316.2).
This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner, a characteristic property of ubiquitin carrier proteins.
Purification Method:
Affinity purification
Gene ID:
27338
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and UBE2S knockout (KO) 293T cells, using [KO Validated] UBE2S Rabbit pAb (CAB18064) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
