The UBE2N/Ubc13 Rabbit Monoclonal Antibody (CAB9257) is a valuable tool for researchers studying the UBE2N/Ubc13 protein, which plays a crucial role in cell cycle regulation and DNA repair processes. This antibody, specifically designed for use in Western blot applications, is highly reactive with human samples and enables the detection and analysis of UBE2N/Ubc13 in various cell types.UBE2N/Ubc13 is an important enzyme involved in the ubiquitination pathway, particularly in the formation of K63-linked polyubiquitin chains.
Dysregulation of UBE2N/Ubc13 has been implicated in various diseases, including cancer and neurodegenerative disorders, making it a promising therapeutic target. By using the UBE2N/Ubc13 Rabbit Monoclonal Antibody, researchers can gain valuable insights into the function and regulation of this protein, advancing our understanding of disease mechanisms and potential treatment strategies.
Product Name:
Ube2N/Ubc13 Rabbit Monoclonal Antibody
SKU:
CAB9257
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Ube2N/Ubc13 (P61088).
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
Purification Method:
Affinity purification
Gene ID:
7334
Clone Number:
ARC1495
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Ube2N/Ubc13 Rabbit mAb (CAB9257) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
