UBE2L3 Rabbit Polyclonal Antibody (CAB4175)
- SKU:
- CAB4175
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | UBE2L3 Rabbit Polyclonal Antibody |
SKU: | CAB4175 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 73-212 of human UBE2L3 (NP_001243284.1). |
Sequence: | RKCG MKNF RNIQ VDEA NLLT WQGL IVPD NPPY DKGA FRIE INFP AEYP FKPP KITF KTKI YHPN IDEK GQVC LPVI SAEN WKPA TKTD QVIQ SLIA LVND PQPE HPLR ADLA EEYS KDRK KFCK NAEE FTKK YGEK RPVD |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | E2-F1; L-UBC; UBCH7; UbcM4; UBE2L3 |
Positive Sample: | U-251MG,HL-60,K-562,HeLa,Mouse testis,Mouse brain,Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 18kDa |
Observed MW: | 18kDa |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7332 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |