UBE2K Rabbit Polyclonal Antibody (CAB1086)
- SKU:
- CAB1086
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | UBE2K Rabbit Polyclonal Antibody |
SKU: | CAB1086 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2K (NP_005330.1). |
Sequence: | MANI AVQR IKRE FKEV LKSE ETSK NQIK VDLV DENF TELR GEIA GPPD TPYE GGRY QLEI KIPE TYPF NPPK VRFI TKIW HPNI SSVT GAIC LDIL KDQW |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LIG; HIP2; HYPG; UBC1; E2-25K; UBE2K |
Positive Sample: | 22Rv1,SKOV3,SW480,HL-60,Raji,U-251MG,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 22kDa |
Observed MW: | 22kDa |
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3093 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |