The UBE2J1 Polyclonal Antibody (CAB15841) is a valuable tool for researchers studying UBE2J1, a protein involved in the ubiquitination pathway. This antibody is produced in rabbits and has been validated for use in Western blot applications with human samples. By binding specifically to the UBE2J1 protein, researchers can accurately detect and analyze this important molecule in various cell types.UBE2J1 is a key player in the ubiquitination process, which is essential for regulating cellular pathways such as protein degradation, signal transduction, and DNA repair. Dysregulation of the ubiquitination pathway has been linked to various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.
Studying UBE2J1 and its interactions can provide insights into these diseases and potentially lead to the development of targeted therapies.With its high reactivity and specificity, the UBE2J1 Polyclonal Antibody is a valuable tool for researchers in the fields of molecular biology, biochemistry, and biomedicine. By accurately detecting and studying UBE2J1, researchers can further our understanding of cellular processes and potentially identify new therapeutic targets.
Product Name:
UBE2J1 Rabbit Polyclonal Antibody
SKU:
CAB15841
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2J1 (NP_057105.2).
Endoplasmic reticulum membrane, Single-pass type IV membrane protein.
Calculated MW:
35kDa
Observed MW:
35kDa
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.
Purification Method:
Affinity purification
Gene ID:
51465
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UBE2J1 Rabbit pAb (CAB15841) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
