The UBE2G2 Polyclonal Antibody (CAB10408) is a vital tool for researchers studying the UBE2G2 protein, which plays a key role in the ubiquitination pathway. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it ideal for use in Western blot applications. By specifically binding to the UBE2G2 protein, researchers can easily detect and analyze its expression in a variety of cell types, facilitating studies in the fields of molecular biology and cancer research.UBE2G2 is a crucial enzyme involved in the regulation of protein degradation through the ubiquitin-proteasome system, making it a potential target for therapeutic interventions in diseases such as cancer and neurodegenerative disorders.
Understanding the functions of UBE2G2 is essential for unraveling the mechanisms of protein turnover and identifying new strategies for treating diseases characterized by dysregulated protein degradation pathways.By utilizing the UBE2G2 Polyclonal Antibody (CAB10408), researchers can gain valuable insights into the molecular mechanisms underlying protein ubiquitination and potentially identify novel therapeutic targets for the development of targeted therapies in the future.
Product Name:
UBE2G2 Rabbit Polyclonal Antibody
SKU:
CAB10408
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human UBE2G2 (NP_003334.2).
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7327
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UBE2G2 antibody (CAB10408) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
