The UBE2E2 Polyclonal Antibody (CAB16441) is a valuable tool for researchers studying UBE2E2, a protein involved in the process of ubiquitination, a key mechanism for regulating protein levels and activity within cells. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot applications. By targeting the UBE2E2 protein, researchers can investigate its function and role in various cellular pathways.UBE2E2 is a member of the ubiquitin-conjugating enzyme family and plays a crucial role in the transfer of ubiquitin molecules to target proteins, marking them for degradation or altering their function.
Understanding the function of UBE2E2 is important for unraveling the complex regulatory networks governing cellular processes such as protein turnover, DNA repair, and cell cycle progression. Research on UBE2E2 is essential for advancing our knowledge of cellular mechanisms and developing potential therapeutic strategies for diseases linked to dysregulated ubiquitination pathways.
Product Name:
UBE2E2 Rabbit Polyclonal Antibody
SKU:
CAB16441
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human UBE2E2 (NP_689866.1).
Enables ISG15 transferase activity and ubiquitin conjugating enzyme activity. Involved in protein modification by small protein conjugation. Acts upstream of or within cellular response to DNA damage stimulus and positive regulation of G1/S transition of mitotic cell cycle. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
7325
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UBE2E2 Rabbit pAb (CAB16441) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
