The UBE2D4 Polyclonal Antibody (CAB8332) is a powerful tool for researchers studying the UBE2D4 protein, a crucial component in the ubiquitination pathway. This antibody, produced in rabbits, exhibits high specificity for human samples and has been rigorously validated for Western blot applications. By binding to the UBE2D4 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an invaluable resource for investigations in areas such as molecular biology and cancer research.UBE2D4, also known as ubiquitin-conjugating enzyme E2D 4, plays a central role in the ubiquitination process, a mechanism essential for protein degradation and regulation within cells.
Dysregulation of the ubiquitination pathway has been implicated in various diseases, including cancer, neurodegenerative disorders, and autoimmune conditions. By understanding the function of UBE2D4, researchers can gain insight into potential therapeutic targets for these ailments, ultimately advancing our understanding of disease mechanisms and treatment strategies.
Product Name:
UBE2D4 Rabbit Polyclonal Antibody
SKU:
CAB8332
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human UBE2D4 (NP_057067.1).
Enables ubiquitin conjugating enzyme activity. Involved in protein polyubiquitination. Acts upstream of or within protein ubiquitination. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
51619
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UBE2D4 antibody (CAB8332) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
