UBE2D2 Rabbit Polyclonal Antibody (CAB10818)
- SKU:
- CAB10818
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | UBE2D2 Rabbit Polyclonal Antibody |
SKU: | CAB10818 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human UBE2D2 (NP_003330.1). |
Sequence: | MALK RIHK ELND LARD PPAQ CSAG PVGD DMFH WQAT IMGP NDSP YQGG VFFL TIHF PTDY PFKP PKVA FTTR IYHP NINS NGSI CLDI LRSQ WSPA LTIS KVLL SICS LLCD PNPD DPLV PEIA RIYK TDRE KYNR IARE WTQK YAM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | UBC4; PUBC1; UBCH4; UBC4/5; UBCH5B; E2(17)KB2; UBE2D2 |
Positive Sample: | U-87MG,K-562,293T,Jurkat,Mouse testis,Mouse brain,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular exosome, nucleoplasm, nucleus |
Calculated MW: | 17kDa |
Observed MW: | 17kDa |
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.
Purification Method: | Affinity purification |
Gene ID: | 7322 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |