UBE2C Rabbit Monoclonal Antibody (CAB5206)
- SKU:
- CAB5206
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | UBE2C Rabbit Monoclonal Antibody |
SKU: | CAB5206 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 70-150 of human UBE2C (O00762). |
Sequence: | AGTV YEDL RYKL SLEF PSGY PYNA PTVK FLTP CYHP NVDT QGNI CLDI LKEK WSAL YDVR TILL SIQS LLGE PNID SPLN T |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | UBCH10; dJ447F3.2; UBE2C |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytosol, Nucleoplasm, Nucleus, Plasma membrane |
Calculated MW: | 20kDa |
Observed MW: | 20kDa |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
Purification Method: | Affinity purification |
Gene ID: | 11065 |
Clone Number: | ARC1166 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |