The UBE2C Polyclonal Antibody is a valuable tool for researchers studying UBE2C, a key enzyme involved in the regulation of cell cycle progression and cell division. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the UBE2C protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for investigations in cancer research and cell biology.UBE2C plays a critical role in maintaining genomic stability and is often dysregulated in various types of cancer, making it a promising target for therapeutic interventions.
By understanding the mechanisms by which UBE2C functions in the cell cycle, researchers can potentially develop novel treatments for cancer and other diseases characterized by abnormal cell proliferation.Overall, the UBE2C Polyclonal Antibody is a valuable tool for researchers interested in exploring the role of UBE2C in cell cycle regulation, cancer development, and potential therapeutic strategies. Its high specificity and reliability make it an essential component of any research project targeting UBE2C.
Product Name:
UBE2C Polyclonal Antibody
SKU:
CAB21347
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 1-179 of human UBE2C (NP_008950.1).
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
Purification Method:
Affinity purification
Gene ID:
11065
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using UBE2C Rabbit pAb (CAB21347) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
