UBE2C Polyclonal Antibody (CAB21347)
- SKU:
- CAB21347
Frequently bought together:
Description
| Product Name: | UBE2C Polyclonal Antibody |
| SKU: | CAB21347 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human |
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 1-179 of human UBE2C (NP_008950.1). |
| Sequence: | MASQ NRDP AATS VAAA RKGA EPSG GAAR GPVG KRLQ QELM TLMM SGDK GISA FPES DNLF KWVG TIHG AAGT VYED LRYK LSLE FPSG YPYN APTV KFLT PCYH PNVD TQGN ICLD ILKE KWSA LYDV RTIL LSIQ SLLG EPNI DSPL NTHA AELW KNPT AFKK YLQE TYSK QVTS QEP |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 |
| Synonyms: | UBCH10; dJ447F3.2; UBE2C |
| Positive Sample: | THP-1,SW620,SK-OV-3 |
| Conjugate: | Unconjugated |
| Cellular Localization: | cytosol, nucleoplasm, nucleus, plasma membrane |
| Calculated MW: | 20kDa |
| Observed MW: | 18kDa |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
| Purification Method: | Affinity purification |
| Gene ID: | 11065 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using UBE2C Rabbit pAb (CAB21347) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s. |
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