UBE2B Rabbit Polyclonal Antibody (CAB6315)
- SKU:
- CAB6315
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | UBE2B Rabbit Polyclonal Antibody |
SKU: | CAB6315 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human UBE2B (NP_003328.1). |
Sequence: | MSTP ARRR LMRD FKRL QEDP PVGV SGAP SENN IMQW NAVI FGPE GTPF EDGT FKLV IEFS EEYP NKPP TVRF LSKM FHPN VYAD GSIC LDIL QNRW SPTY DVSS ILTS IQSL LDEP NPNS PANS QAAQ LYQE NKRE YEKR VSAI VEQS WNDS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HR6B; UBC2; HHR6B; RAD6B; E2-17kDa; UBE2B |
Positive Sample: | MCF7,SW480,Jurkat,NIH/3T3,Mouse heart,Mouse brain,Mouse skeletal muscle,Rat heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Nucleus. |
Calculated MW: | 17kDa |
Observed MW: | 16kDa |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
Purification Method: | Affinity purification |
Gene ID: | 7320 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |