The UBASH3B Polyclonal Antibody (CAB7141) is a valuable tool for researchers studying UBASH3B, a protein involved in immune regulation and signaling pathways. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the UBASH3B protein, this antibody enables accurate detection and analysis in a variety of cell types, making it perfect for studies in immunology and cancer research.UBASH3B, also known as T-cell ubiquitin ligand, plays a crucial role in immune responses by regulating signaling pathways and modulating immune cell functions.
Its importance in immune system regulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions. By understanding the function of UBASH3B, researchers can develop new therapies that target or manipulate immune responses in these disease contexts.
Product Name:
UBASH3B Rabbit Polyclonal Antibody
SKU:
CAB7141
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human UBASH3B (NP_116262.2).
This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.
Purification Method:
Affinity purification
Gene ID:
84959
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using UBASH3B Rabbit pAb (CAB7141) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
