The UBA5 Polyclonal Antibody (CAB15514) is a valuable tool for researchers studying the UBA5 protein, which plays a crucial role in protein modification and cellular signaling pathways. This antibody, produced in rabbits, has been rigorously tested and validated for use in Western blot applications with human samples.UBA5 is a key enzyme involved in the process of ufmylation, a post-translational modification that regulates protein stability, localization, and function. Dysregulation of ufmylation has been linked to various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
By targeting UBA5 with this antibody, researchers can gain valuable insights into the mechanisms underlying these pathologies and potentially identify novel therapeutic targets.With its high reactivity and specificity, the UBA5 Polyclonal Antibody is a versatile tool for investigating the role of UBA5 in various cellular processes and disease pathologies. Its application in Western blot analysis makes it an essential component of any research study focused on understanding the complex functions of the UBA5 protein.
Product Name:
UBA5 Rabbit Polyclonal Antibody
SKU:
CAB15514
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-404 of human UBA5 (NP_079094.1).
This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1.
Purification Method:
Affinity purification
Gene ID:
79876
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using UBA5 Rabbit pAb (CAB15514) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
