The UBA1 Rabbit Monoclonal Antibody (CAB9254) is a highly specific tool for researchers studying the ubiquitin-activating enzyme 1 (UBA1) protein. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in a variety of applications, including Western blotting.UBA1 is a critical enzyme involved in the ubiquitination pathway, which regulates protein degradation and signaling within cells. Dysregulation of ubiquitination has been linked to various diseases, including cancer, neurodegenerative disorders, and autoimmune conditions.
The UBA1 Rabbit Monoclonal Antibody enables researchers to detect and analyze UBA1 expression in different cell types, providing valuable insights into its role in health and disease.By targeting UBA1, researchers can explore novel therapeutic targets and develop treatments for conditions associated with dysregulated protein homeostasis. This antibody is an essential tool for advancing research in the fields of molecular biology, cell biology, and drug discovery.
Product Name:
UBA1 Rabbit Monoclonal Antibody
SKU:
CAB9254
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 959-1058 of human UBA1 (P22314).
The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Purification Method:
Affinity purification
Gene ID:
7317
Clone Number:
ARC1493
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using UBA1 Rabbit mAb (CAB9254) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
