UACA Rabbit Polyclonal Antibody (CAB9713)
- SKU:
- CAB9713
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | UACA Rabbit Polyclonal Antibody |
SKU: | CAB9713 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human UACA (NP_060473.2). |
Sequence: | MKSL KSRL RRQD VPGP ASSG AAAA SAHA ADWN KYDD RLMK AAER GDVE KVTS ILAK KGVN PGKL DVEG RSVF HVVT SKGN LECL NAIL IH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NUCLING; UACA |
Positive Sample: | U-87MG,293T,HT-1080,SKOV3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, cytoskeleton. |
Calculated MW: | 163kDa |
Observed MW: | 162kDa |
This gene encodes a protein that contains ankyrin repeats and coiled coil domains and likely plays a role in apoptosis. Studies in rodents have implicated the encoded protein in the stimulation of apoptosis and the regulation of mammary gland involution, in which the mammary gland returns to its pre-pregnant state. This protein has also been proposed to negatively regulate apoptosis based on experiments in human cell lines in which the protein was shown to interact with PRKC apoptosis WT1 regulator protein, also known as PAR-4, and inhibit translocation of the PAR-4 receptor. Autoantibodies to this protein have been identified in human patients with panuveitis and Graves' disease. Differential expression of this gene has been observed in various human cancers.
Purification Method: | Affinity purification |
Gene ID: | 55075 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |