U2AF2/U2AF65 Rabbit Polyclonal Antibody (CAB1936)
- SKU:
- CAB1936
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | U2AF2/U2AF65 Rabbit Polyclonal Antibody |
SKU: | CAB1936 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 192-471 of human U2AF2/U2AF65 (NP_001012496.1). |
Sequence: | NQDK NFAF LEFR SVDE TTQA MAFD GIIF QGQS LKIR RPHD YQPL PGMS ENPS VYVP GVVS TVVP DSAH KLFI GGLP NYLN DDQV KELL TSFG PLKA FNLV KDSA TGLS KGYA FCEY VDIN VTDQ AIAG LNGM QLGD KKLL VQRA SVGA KNAT LSTI NQTP VTLQ VPGL MSSQ VQMG GHPT EVLC LMNM VLPE ELLD DEEY EEIV EDVR DECS KYGL VKSI EIPR PVDG VEVP GCGK IFVE FTSV FDCQ KAMQ GLTG RKFA NRVV VTKY CDPD SYHR RDFW |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | U2AF65; U2AF2/U2AF65 |
Positive Sample: | Jurkat,SW620,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 54kDa |
Observed MW: | 54kDa |
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
Purification Method: | Affinity purification |
Gene ID: | 11338 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |