Tyrosine Hydroxylase Rabbit Monoclonal Antibody (CAB5079)
- SKU:
- CAB5079
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DYT14
- DYT5b
- TYH
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Tyrosine Hydroxylase Rabbit Monoclonal Antibody |
SKU: | CAB5079 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Tyrosine Hydroxylase (P07101). |
Sequence: | MPTP DATT PQAK GFRR AVSE LDAK QAEA IMVR GQGA PGPS LTGS PWPG TAAP AASY TPTP RSPR FIGR RQSL IEDA RKER EAAV AAAA AAVP SEPG DPLE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TYH; DYT14; DYT5b; Tyrosine Hydroxylase |
Positive Sample: | SH-SY5Y,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | axon, cytoplasm, cytoplasmic side of plasma membrane, cytoplasmic vesicle, cytosol, dendrite, mitochondrion, neuron projection, nucleus, perikaryon, perinuclear region of cytoplasm, smooth endoplasmic reticulum, synaptic vesicle, terminal bouton |
Calculated MW: | 59kDa |
Observed MW: | 59kDa |
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7054 |
Clone Number: | ARC1184 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |