Tyrosinase Polyclonal Antibody (CAB11988)
- SKU:
- CAB11988
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Tyrosinase Polyclonal Antibody |
SKU: | CAB11988 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-455 of human Tyrosinase (NP_000363.1). |
Sequence: | HFPR ACVS SKNL MEKE CCPP WSGD RSPC GQLS GRGS CQNI LLSN APLG PQFP FTGV DDRE SWPS VFYN RTCQ CSGN FMGF NCGN CKFG FWGP NCTE RRLL VRRN IFDL SAPE KDKF FAYL TLAK HTIS SDYV IPIG TYGQ MKNG STPM FNDI NIYD LFVW MHYY VSMD ALLG GSEI WRDI DFAH EAPA FLPW HRLF LLRW EQEI QKLT GDEN FTIP YWDW RDAE KCDI CTDE YMGG QHPT NPNL LSPA SFFS SWQI VCSR LEEY NSHQ SLCN GTPE GPLR RNPG NHDK SRTP RLPS SADV EFCL SLTQ YESG SMDK AANF SFRN TLEG FASP LTGI ADAS QSSM HNAL HIYM NGTM SQVQ GSAN DPIF LLHH AFVD SIFE QWLR RHRP LQEV YPEA NAPI GHNR ESYM VPFI PLYR NGDF FISS KDLG YDYS YLQD S |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:1000 - 1:5000 |
Synonyms: | ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3; Tyrosinase |
Conjugate: | Unconjugated |
Cellular Localization: | Melanosome membrane, Single-pass type I membrane protein. |
Calculated MW: | 60kDa |
Observed MW: | Refer to figures |
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Purification Method: | Affinity purification |
Gene ID: | 7299 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |