The Tyrosinase Monoclonal Antibody (CAB23209) is a valuable tool for researchers studying tyrosinase, an enzyme involved in the production of melanin. This antibody, developed using a monoclonal approach, has high specificity and sensitivity for detecting tyrosinase in various samples. It is ideal for use in techniques such as Western blot and immunohistochemistry, allowing for accurate and reliable analysis of tyrosinase expression in cells and tissues.Tyrosinase plays a crucial role in melanin synthesis, making it an important target for research in areas such as dermatology, cosmetology, and oncology.
By utilizing the Tyrosinase Monoclonal Antibody, researchers can further understand the function and regulation of this enzyme, leading to advancements in treatments for skin pigmentation disorders, melanoma, and other related conditions.Overall, the Tyrosinase Monoclonal Antibody (CAB23209) offers a precise tool for investigating the role of tyrosinase in various biological processes, contributing to the development of new therapeutic strategies and diagnostic tools in related fields.
Product Name:
Tyrosinase Monoclonal Antibody
SKU:
CAB23209
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Tyrosinase (NP_000363.1).
Melanosome membrane, Single-pass type I membrane protein.
Calculated MW:
60kDa
Observed MW:
Refer to figures
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Purification Method:
Affinity purification
Gene ID:
7299
Clone Number:
ARC53165
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of Tyrosinase in paraffin-embedded Human malignant melanoma using Tyrosinase Rabbit mAb (CAB23209) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
